Research

Clinical Trials

NIH (NINDS)   —   R01NS073717 
Alberts, Jay 
“The Cyclical Lower-Extremity Exercise (CYCLE) for Parkinson’s Trial” 

NIH (NIAMS)   —   R01AR068342 
Derwin, Kathleen / Iannotti, Joseph 
“Failure with Continuity and its Relation to Rotator Cuff Repair Clinical Outcomes” 

NIH (NIAMS)   —   R01AR077452 
Li, Xiaojuan 
“Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry” 

NIH (NIAMS)   —   R01AR074131 
Spindler, Kurt 
“BEAR-MOON: A Two Arm Noninferiority Blinded Randomized Clinical Trial Comparing ACL Repair with BEAR Device vs. Standard of Care Autograft Patellar Tendon ACL Reconstruction” 

NIH (NIAMS)   —   R01AR075422 
Li, Xiaojuan 
“Imaging post-traumatic osteoarthritis 10-years after ACL reconstruction: a multicenter cohort study with quantitative MRI” 

NIH (NICHD)   —   K01HD092556 
Linder, Susan 
“Cost-effectiveness and efficacy of a combined intervention to facilitate motor recovery following stroke” 

NIH (NIAMS)   —   R21AR078401 
Derwin, Kathleen 
“Variation in Humeral Head Bone Marrow Characteristics and Their Associations with Rotator Cuff Repair Healing” 

NIH (NIAMS)   —   R01AR055557 (sub-award) 
Spindler, Kurt 
“Partial Meniscectomy versus Nonoperative Management in Meniscal Tear with OA: An RCT” 

NIH (NINDS)   —   U01NS113851 (sub-award) 
Alberts, Jay 
“Study in Parkinson Disease of Exercise Phase 3 Clinical Trial: SPARX3” 

NIH (NIAMS)   —   U01AR080377 (sub-award) 
Piuzzi, Nicolas 
“HIP ATTACK-2 trial (HIP fracture Accelerated surgical care and TreaTment trACK) 2” 

Grants

$10.4 Million
Total Grant Funding (2022)

Federal Grants

NIH (NCCIH)   —   R01AT011905 
Marasco, Paul 
“Sensing active movement of the self: reconsidering the cellular basis kinesthesia”  

NIH (NIAMS)   —   R01AR073225 
Streubel, Philipp 
“3D bioprinting of biomimetic constructs for rotator cuff augmentation”  

NIH (NIBIB)   —   R01EB025212 
Erdemir, Ahmet 
"Software for Practical Annotation and Exchange of Virtual Anatomy"  

NIH (NIDCR)   —   R01DE029634 
Muschler, George 
"Understanding and Using Variation in Source Materials for MSC Fabrication"  

NIH (NIAMS)   —   R01AR077452 
Li, Xiaojuan 
"Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry"  

NIH (NIAMS)   —   R01AR075422 
Li, Xiaojuan 
"Imaging post-traumatic osteoarthritis 10-years after ACL reconstruction: a multicenter cohort study with quantitative MRI"  

NIH (NIAMS)   —   R01AR068342 
Derwin, Kathleen / Iannotti, Joseph 
"Failure with Continuity and its Relation to Rotator Cuff Repair Clinical Outcomes"  

NIH (NINDS)   —   R01NS073717 
Alberts, Jay 
"CYClical Lower Extremity exercise for Parkinsons trial (CYCLE Trial)"  

NIH (NIAMS)   —   R01AR074131 
Spindler, Kurt 
"BEAR-MOON: A Two Arm Noninferiority Blinded Randomized Clinical Trial Comparing ACL Repair with BEAR Device vs. Standard of Care Autograft Patellar Tendon ACL Reconstruction"  

NIH (NIAMS)   —   R01AR075286 
Ricchetti, Eric 
"Identifying the Patient, Disease, Surgical, and Implant Positional Shift Factors that Predict Outcomes Following Total Shoulder Arthroplasty"  

NIH (NIAMS)   —   R13AR076258 
Spindler, Kurt 
"Clinician Scholar Career Development Program (CSCDP)"  

NIH (NIAMS)   —   R21AR078498 
Apte, Suneel 
“The proteolytic landscape of osteoarthritic cartilage”  

NIH (NIAMS)   —   R21AR078401 
Derwin, Kathleen 
“Variation in Humeral Head Bone Marrow Characteristics and Their Associations with Rotator Cuff Repair Healing”  

NIH (NINDS)   —   R21NS129147 
Alberts, Jay 
“The impact of exercise on subthalamic nucleus neural activity in Parkinson's disease”  

NIH (NICHD)   —   K01HD092556 
Linder, Susan 
“Cost-effectiveness and efficacy of a combined intervention to facilitate motor recovery following stroke”  

NIH (NIAMS)   —   K25AR078928 
Yang, Mingrui 
“Automated Arthroscopic Partial Meniscectomy Patient Outcome Prediction using Deep Learning”  

NIH (NIAMS)   —   R01AR055557 (sub-award) 
Spindler, Kurt 
“Partial Meniscectomy vs. NonOperative Management in Meniscal Tear with OA: An RCT”  

NIH (NIAMS)   —   U01AR080377 (sub-award) 
Piuzzi, Nicolas 
“HIP ATTACK-2 trial (HIP fracture Accelerated surgical care and TreaTment trACK) 2”  

NIH (NINDS)   —   U01NS113851 (sub-award) 
Alberts, Jay 
"Study in Parkinson Disease of Exercise Phase 3 Clinical Trial: SPARX3" 

Innovations

US PATENTS

Vijay Krishna, Sanjay Anand, Edward Maytin, Stephen Grobmyer: "Polyhydroxy fullerene sunscreen active agents and compositions". US Patent No: 11,957,769, granted Apr 2024.

Kathleen Derwin, Amit Aurora, Joseph P. Iannotti, Jesse A. McCarron: "Reinforced tissue graft". US Patent No: 11,951,232; granted Apr 2024.

Robert Assell, Andy Freeman, George Muschler: "Bone fragment and tissue processing system". US Patent No: 11,931,087; granted Mar 2024.

Jay L. Alberts, David D. Schindler, Jane Rhodes, Wendy Gabel, Jim Best: "Apparatus and related method to facilitate test via a computing device". US Patent No: 11,857,349; granted Jan 2024.

Muschler GF, Monnich JK, Kwee EJ, Powell KA, Herderick EE, Boehm CA, Adams TR, Germanoski R, Krakosh III F, Dunn J, Bantz D: "Systems and methods for detection, analysis, isolation and/or harvesting of biological objects". US Patent No: 11,579,160; granted Feb 2023.

McCrae K, Merkulov S, Alluri RK: "Human β2-glycoprotein I expression".  US Patent No: 11,661,447; granted May 2023.

Colbrunn R, Nagle T, Gillespie C: "Hybrid control of a robotic system". US Patent No: 11,691,280; granted Jul 2023.

Iannotti JP, Barsoum WK, Bryan JA, O'Neill PD: "System and method for association of a guiding aid with a patient tissue". US Patent No: 11,730,497; granted Aug 2023.

Gillespie C, Colbrunn R, Nagle T: "Compliance correction in a robotic system". US Patent No: 11,745,341; granted Sep 2023.

Assell R, Freeman A, Muschler G: "Bone void filler preparation system". US Patent No: 11,850,326; granted Dec 2023.

Assell R, Freeman A, Muschler GF: "Bone fragment and tissue harvesting system". US Patent No: 11,337,710; granted May 2022.

Baker JJ, Gingras PH, Priest R, Derwin K, Iannotti JP, Sahoo S, Baker AR: "Radiopaque tissue marker". US Patent No: 11,413,112; granted Aug 2022.

Schoenhagen P, Chen PH, Piraino D, Obuchowski N: "Automated identification of acute aortic syndromes in computed tomography images". US Patent No: 11,475,561; granted Oct 2022.

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Pilot Project Programs

The Musculoskeletal Research Center's Pilot Project Program for Cleveland Clinic investigators is available to support currently unfunded, novel, particularly innovative, disease-oriented projects that are in need of the early data that would make them competitive for extramural funding. Funding will be available to support projects along the entire continuum of biomedical investigation, including discovery, translation and direct patient-involved research.

Two types of awards of up to $25,000 each are available: (1) MSRC General awards are for musculoskeletal research projects on any topic related to musculoskeletal research, and (2) MSRC MSK Imaging awards are for musculoskeletal imaging research projects. Announcement of funding opportunity will be made to MSRC members via email.

InfoReady Review is used to manage Pilot Project submissions. Each competition will be launched on the InfoReady Review home page one month prior to the deadline. If you have any issues submitting an application, please contact us.

General Funded Projects

• Suneel Apte, MBBS, DPhil: "Synovial fluid degradomics for discovery of proteolytic pathways and biomarkers in juvenile idiopathic arthritis" (September 2023)
• Sambit Sahoo, MD, PhD: "Characterizing patient reported outcome measures (PROMs) following RCR" (September 2023)
• Anabelle Visperas, PhD: “In Depth Proteomic and Transcriptomic Analysis of Periprosthetic Joint Infection.” (September 2022)
• Megan Jack, MD, PhD: “The Role of Exercise on Macrophage Polarization at the Neuromuscular Junction Following Peripheral Nerve Injury.” (September 2022)
• Unnikrishnan Chandrasekharan, PhD: "Protein arginine methyltransferase 5 (PRMT5), a novel drug target of inflammatory arthritis and cardiovascular comorbidity." (March 2021)
• Jillian Beveridge, PhD: "Computational Modeling of In Vivo ACL Function" (September 2020)
• Suneel Apte, MBBS, DPhil: "Proteome-wide analysis of cartilage degradation in knee OA" (March 2020)
• Carlos Higuera-Rueda, MD: "Efficacy of MagDAA gel on disruption of established bacterial biofilm in a rabbit model of periprosthetic joint infection (PJI)" (March 2019)

MSK Imaging Funded Projects

• Lauren Wichman, MD: "Does Energy Deficiency Contribute to Knee Injuries in Female Athletes? (March 2025)"
• D. Patrick Corrigan, PhD: "Identifying muscle characteristics related to impaired physical function and altered walking biomechanics in adults with knee osteoarthritis" (March 2025)
• Kihwan Kim: "Investigation of the effect of semaglutide treatment on muscle metabolic function using phosporus-31 magnetic resonances spectroscopy" (November 2024)
• Aaron Lear, MD: “Identifying Factors Contributing to Cartilage Degradation for Adolescents with Patellofemoral Pain.” (September 2022)
• Saeid Mirzai, DO: “Secondary Sarcopenia from Heart Failure: The Value of Imaging Modalities for its Diagnosis and Rehabilitation for its Management.” (September 2022)
• Stefan Zbyn, PhD: “Characterization of Cartilage and Meniscus Degeneration by Morphological and Quantitative Magnetic Resonance Imaging with Ultra-high Spatial Resolution at 7 Tesla.” (September 2022)
• Sibaji Gaj, PhD: "Novel automated lesion segmentation in post-traumatic osteoarthritis using unsupervised deep-learning methods" (March 2022)
• Bong-Jae Jun, PhD: "Characterization of Post-Traumatic Osteoarthritis (PTOA) Following anterior cruciate ligament reconstruction (ACLR) using cone-beam computed tomography (CBCT) imaging" (September 2021)
• Ceylan Colak, MD and Richard Lartey, PhD: "Optimizing Non-Contrast Magnetic Resonance Imaging (MRI) Sequences for Knee Synovitis" (Junior Investigator, September 2020)
• Maryam Zokaeinikoo, PhD: "Automated knee radiograph analysis using deep-learning techniques" (Junior Investigator, September 2020)
• Brendan Eck, PhD: "Characterization of sarcopenia by magnetic resonance fingerprinting and phosphorous magnetic resonance spectroscopic imaging" (Junior Investigator, September 2019)
• Jinjin Ma, PhD: "Investigating MR Biomarkers of Bone Marrow Quality in Musculoskeletal Disease" (Junior Investigator, September 2018)
• Mingrui Yang, PhD: "Automated Arthroscopic Partial Meniscectomy Patient Outcome Prediction using Deep Learning" (Junior Investigator, September 2018)
• Nicholas Piuzzi, MD: "A Comparative and Correlative Evaluation of Early to Late Stage Osteoarthritis in Human Knee Cartilage utilizing Clinical and Preclinical MRI Imaging (3T & 7T) with Histopathology and Immunohistochemistry as the Standard" (Junior Investigator, March 2018)
• John Elias, PhD:  "Optimizing Surgical Stabilization for Patellar Instability to Reduce the Risk of Arthritis" (Established Investigator, March 2018)

Other Resources

• Program for Advanced Musculoskeletal Imaging (PAMI)
• Lerner Research Institute Research Core Services
• Clinical Research Unit (CRU)
• Cleveland Clinic Innovations (CCI)

Amy & David Krohn Family Orthopaedic Outcomes Center

The Amy and David Krohn Family Orthopaedic Outcomes Center (OOC) is an arm of the Cleveland Clinic Musculoskeletal Research Center (MSRC) focusing primarily on the clinical outcomes of orthopaedic surgery and related treatments. Bringing together the expertise of orthopaedic clinicians, researchers, data scientists, and statisticians, the OOC endeavors to:

• Develop and implement the technical and logistical infrastructure to systematically collect, analyze, and publish data related to clinical and patient-reported outcome measures (PROMs) with a focus on joint replacement, sports injuries, and shoulder and upper extremity surgery
• Guide the development and implementation of grants and research projects related to orthopaedic outcomes
• Secure commercial contracts related to outcomes data collection and reporting
• Support departmental quality initiatives and outcomes publishing on the Cleveland Clinic Outcomes website

About Us

Members

• Kurt Spindler, MD: OOC Director
• Elizabeth Sosic, BS: OME Program Manager
• Greg Strnad, MS: Lead Database Designer
• Sage O'Bryant, BS: System Analyst
• Brittany Stojsavljevic, BA: Editorial Assistant
• Aretha Siggers, BS: Research Assistant
• Sonja Ealy, BS: Research Assistant
• LaTashua Manning, BS: Research Assistant
• Charlotte Gapas, MBA: Research Assistant

Outcomes Management and Evaluation

Overview

The OOC's flagship service is the Outcomes Management and Evaluation (OME) system, which is used across the institution to systematically collect patient-reported outcome measures (PROMs) in a highly structured and consistent manner. OME is a cost-effective, scientifically valid, scalable electronic system for collecting PROMs and clinical information surrounding an episode of care:

• Cost-effective: makes use of commodity hardware, built into existing workflow
• Scientifically valid: 95%+ baseline enrollment and 70%+ 1-year follow-up helps prevent bias, and usage of validated PROMs ensures results can be consistent with the scientific literature
• Scalable: ability to handle high patient volumes across a wide range of interventions, and operate seamlessly within Cleveland Clinic locations regardless of geographic dispersion as well as with outside institutions for multicenter collaboration

Initially launched in 2015 an "Episode of Care" supplement to the OOC's former OrthoMiDaS system, OME has since supplanted OrthoMiDaS to establish itself as the de-facto data collection mechanism for orthopaedic surgery. The data collected through this system feeds the OME Cohort, a powerful prospective cohort that supports standard of care, quality initiatives, and three primary points of research focus:

1. Determine patient and clinical factors that predict patient-reported pain and function prior to orthopaedic surgery
2. Determine predictors of patient-reported and clinical outcomes one year after orthopaedic surgery
3. Compare 1- and 2-year patient-reported outcomes of orthopaedic surgery

Current Enrollment

As of August 2019, OME is active at 16 Cleveland Clinic hospitals and ASCs and covers over 95% of elective orthopaedic surgery cases performed on the knee, hip, and shoulder, ranging from arthroscopy to arthroplasty. OME is also used in select spine, hand, wrist, foot, and ankle surgeries, as well as for patients receiving non-surgical orthobiologic treatment and patients undergoing MRI scans for sports injuries. Over 45,000 episodes of care representing over 40,000 patients have been collected to date with average baseline PROM completion rates of over 95% and 1-year follow-up PROM completion rates of over 70%. Additional orthopaedic and non-orthopaedic procedures are being added to the OME portfolio regularly.

Publications

• Validity and efficiency of a smartphone-based electronic data collection tool for operative data in rotator cuff repair. Sambit Sahoo MD PhD, Jill Mohr BS, Gregory J. Strnad MS, José Vega MA, Morgan Jones MD MPH, Mark S. Schickendantz MD, Lutul Farrow MD, Kurt P. Spindler MD, Joseph P. Iannotti MD PhD, Eric T. Ricchetti MD, Kathleen A. Derwin PhD. Journal of Shoulder and Elbow Surgery, July 2019.
• Predicting the Need for Surgical Intervention Prior to First Encounter for Individuals With Knee Complaints: A Novel Approach. José F. Vega MA, Gregory J. Strnad MS, James Bena MS, Kurt P. Spindler MD. Orthopaedic Journal of Sports Medicine, July, 2019.
• Arthroplasty studies with greater than 1000 participants: analysis of follow-up methods. Muhammad B. Tariq BS, José F. Vega MA, Robert Westermann MD, Morgan Jones MD MPH, Kurt P. Spindler MD. Arthroplasty Today, June 2019.
• A smart decision: smartphone use for operative data collection in arthroscopic shoulder instability surgery. Jill Mohr, Gregory J Strnad, Lutul Farrow, Kate Heinlein, Carolyn M Hettrich, Morgan H Jones, Anthony Miniaci, Eric Ricchetti, James Rosneck, Mark Schickendantz, Paul Saluan, José F Vega, Kurt P Spindler. Journal of the American Medical Informatics Association, June 2019.
• The Main Predictors of Length of Stay After Total Knee Arthroplasty: Patient-Related or Procedure-Related Risk Factors. Nicolas Piuzzi, Gregory Strnad, Wael Ali Sakr Esa, Wael Barsoum, Michael Bloomfield, Peter Brooks, Carlos Higuera-Rueda, Michael Joyce, Michael Kattan, Alison Klika, Viktor Krebs, Nathan Mesko, Michael Mont, Trevor Murray, George Muschler, Robert Nickodem, Preetesh Patel, Jonathan Schaffer, Kurt Spindler, Kim Stearns, Juan Suarez, Alexander Zajichek, Robert Molloy. The Journal of Bone & Joint Surgery, June 2019.
• Predictors of Pain and Function Before Knee Arthroscopy. Cleveland Clinic Sports Knee Group, Matthew C Bessette MD, Robert W. Westermann MD, Alan Davis MD, Lutul Farrow MD, Mia S. Hagen MD, Anthony Miniaci MD, Robert Nickodem MD, Richard Parker MD, James Rosneck MD, Paul Saluan MD, Kurt P. Spindler MD, Kim Stearns MD, Morgan H. Jones MD MPH. Orthopaedic Journal of Sports Medicine, May, 2019.
• Prospective Evaluation of the Patient Acceptable Symptom State to Identify Clinically Successful Anterior Cruciate Ligament Reconstruction. Vega JF, Jacobs CA, Strnad GJ, Farrow L, Jones MH, Miniaci A, Parker RD, Rosneck J, Saluan P, Williams JS, Spindler KP. American Journal of Sports Medicine, April 2019.
• Does Patient Experience After a Total Knee Arthroplasty Predict Readmission? Nipun Sodhi MD, Michael A. Mont MD, Cleveland Clinic Orthopaedic Arthroplasty. The Journal of Arthroplasty, April, 2019.
• Implementing a Scientifically Valid, Cost-Effective, and Scalable Data Collection System at Point of Care: The Cleveland Clinic OME Cohort. Nicolas Piuzzi, Greg Strnad, Peter Brooks, Carolyn Hettrich, Carlos Higuera-Rueda, Joseph Iannotti, Michael Kattan, Robert Molloy, T. Lynch, Alex Milinovich, Eric Ricchetti, James Rosneck, Mark Schickendantz, Kurt Spindler. The Journal of Bone and Joint Surgery, March 2019.
• Comparison of Standard and Right/Left International Knee Documentation Committee Subjective Knee Form Scores. Justin A. Magnuson BA, Greg Strnad MS, Clair Smith MS, Morgan H. Jones MPH MD, Paul Saluan MD, James J. Irrgang PT PhD ATC FAPTA, Kurt P. Spindler MD. The American Journal of Sports Medicine, March 2019.
• Tear characteristics and surgeon influence repair technique and suture anchor use in repair of superior-posterior rotator cuff tendon tears. Kathleen A. Derwin PhD, Sambit Sahoo MD PhD, Alexander Zajichek MS, Gregory Strnad MS, Kurt P. Spindler MD, Joseph P. Iannotti MD PhD, Eric T. Ricchetti MD. Journal of Shoulder and Elbow Surgery, February 2019.
• Validation of a Novel Surgical Data Capturing System After Hip Arthroscopy. Brown MC, Westermann RW, Hagen MS, Strnad GJ, Rosneck JT, Spindler KP, Lynch TS. Journal of the American Academy of Orthopaedic Surgeons, February 2019.
• A National Collegiate Athletic Association Division I Athlete's Return to Play After Traumatic Knee Dislocation With Vascular and Nerve Injury. Michael Kolosky DO, Kurt Spindler MD. JAAOS Global Research & Reviews, November, 2018.
• Validation of a Novel Surgical Data Capturing System Following Total Hip Arthroplasty. Gannon L. Curtis MD, Muhammad B. Tariq MD, David P. Brigati MD, Mhamad Faour MD, Carlos A. Higuera MD, Cleveland Clinic Orthopaedic Arthroplasty Group. The Journal of Arthroplasty, November, 2018.
• Birmingham hip resurfacing versus cementless total hip arthroplasty in patients 55 years or younger: A minimum five-year follow-up. Mohamad J. Halawi, Sameer R. Oak, David Brigati, Aretha Siggers, William Messner, Peter J. Brooks. Journal of Clinical Orthopaedics and Trauma, October, 2018.
• No Difference in Outcomes 12 and 24 Months After Lower Extremity Total Joint Arthroplasty: A Systematic Review and Meta-Analysis. Prem N. Ramkumar MD MBA, Sergio M. Navarro BS, Heather S. Haeberle BS, Mitchell Ng BS, Nicolas S. Piuzzi MD, Kurt P. Spindler MD. The Journal of Arthroplasty, July, 2018.
• The Association Between Readmission and Patient Experience in a Total Hip Arthroplasty Population. Cleveland Clinic Orthopaedic Arthroplasty: Jay M. Levin, BA, Anton Khlopas, MD, Nipun Sodhi, BA, Assem A. Sultan, MD, Morad Chughtai, MD, Wael K. Barsoum, MD, Damien Billow, MD, Michael R. Bloomfield, MD, Daniel Bokar, Peter J. Brooks, MD, Peter J. Evans, MD, Gregory J. Gilot, MD, Carlos A. Higuera, MD, Joseph P. Iannotti, MD, Michael J. Joyce, MD, Michael Kattan, Carmen Kestranek, Viktor E. Krebs, MD, Nathan W. Mesko, MD, John McLaughlin, DO, Anthony Miniaci, MD, Robert M. Molloy, MD, Trevor G. Murray, MD, George F. Muschler, MD, Robert Nickodem, MD, Lukas M. Nystrom, MD, Preetesh D. Patel, MD, Nicolas S. Piuzzi, MD, Kevin Phipps, Eric T. Ricchetti, MD, Susannah Rose, PhD, James Rosneck, MD, Jonathan L. Schaffer, MD, William H. Seitz Jr., MD, Elizabeth Sosic, Kurt P. Spindler, MD, Kim L. Stearns, MD, Greg Strnad, MS, Juan C. Suarez, MD, Michael A. Mont, MD. The Journal of Arthroplasty, June, 2018.
• Validation of a New Web-Based System for Point-of-Care Implant Documentation in Total Knee Arthroplasty. Deepak Ramanathan MD, Bishoy V. Gad MD, Matthew R. Luckett MD, Alison K. Klika MS, Kurt P. Spindler MD, Carlos A. Higuera MD. The Journal of Knee Surgery. December, 2017.
• Predictors of Hip Pain and Function in Femoroacetabular Impingement: A Prospective Cohort Analysis. Robert W. Westermann MD, T. Sean Lynch MD, Morgan H. Jones MD MPH, Kurt P. Spindler MD, William Messner PhD, Greg Strnad MS, and James Rosneck MD. Orthopaedic Journal of Sports Medicine, September, 2017.
• Responsiveness Comparison of the EQ-5D, PROMIS Global Health, and VR-12 Questionnaires in Knee Arthroscopy. Sameer R. Oak MD, Gregory J. Strnad MS, James Bena MS, Lutul D. Farrow MD, Richard D. Parker MD, Morgan H. Jones MD, and Kurt P. Spindler MD. Orthopaedic Journal of Sports Medicine, December 17, 2016.

Publication Tracker (FINER Form)

Grants

BEAR-MOON
Multicenter FDA trial funded by NIH/NIAMS comparing the BEAR® scaffold for ACL repair to standard of care ACL reconstruction
https://bearmoon.org

Members

MSRC Steering Committee

Lerner Research Institute

• Biomedical Engineering
  • Jay Alberts, PhD
  • Suneel Apte, DPhil
  • Kathleen Derwin, PhD
  • Ahmet Erdemir, PhD
  • David Escobar, PhD
  • Bong-Jae Jun, PhD
  • Mandy Koop, PhD
  • Vijay Krishna, PhD
  • Richard Lartey, PhD
  • Xiaojuan Li, PhD
  • Jia Liu, PhD
  • Paul Marasco, PhD
  • Kunio Nakamura, PhD
  • Carl Saab, PhD
  • Sambit Sahoo, MD, PhD
  • Mingrui Yang, PhD
  • Stefan Zbyn, PhD
• Cancer Biology
  • Rebecca Anderson, PhD
• Cardiovascular & Metabolic Sciences
  • Unni Chandrasekharan, PhD
  • Mitali Das, PhD
  • Keith McCrae, MD
  • Sujay Subbayya Ithychanda, PhD
• Department of Research (Akron General)
  • John Elias, PhD
  • Joseph Gabra, DEng
• Immunotherapy & Precision Immuno-Oncology
  • Dongxu Jiang, PhD
• Infection Biology
  • Weiqiang (Javier) Chen, PhD
• Quantitative Health Sciences
  • Jarrod Dalton, PhD
  • Peter Imrey, PhD
  • Brittany Lapin, PhD
  • Nancy Obuchowski, PhD
• Research Core Services
  • Robb Colbrunn, DEng
  • Tara Nagle, PhD

Surgical Specialty

• Orthopaedic Surgery
  • Damien Billow, MD
  • Michael Bloomfield, MD
  • Georgeanne Botek, DPM
  • Zachary Burke, MD
  • Sagar Chawla, MD
  • Matthew Deren, MD
  • Vahid Entezari, MD
  • Lutul Farrow, MD
  • Jason Genin, DO
  • Ryan Goodwin, MD
  • Emily Graydon, PA-C
  • Jason Ho, MD
  • Matthew Kampert, DO
  • Dominic King, DO
  • Steven Maschke, MD
  • Nate Mesko, MD
  • Robert Molloy, MD
  • George Muschler, MD
  • Lukas Nystrom, MD
  • Richard Parker, MD
  • Nicolas Piuzzi, MD
  • Eric Ricchetti, MD
  • Sami Rifat, MD
  • Paul Saluan, MD 
  • Jonathan Schaffer, MD, MBA
  • Mark Schickendantz, MD
  • Kurt Spindler, MD 
  • Yirka Vacca, PA-C
  • Heather Vallier, MD
  • Anabelle Visperas, PhD
• Orthopaedic Surgery (Akron General)
  • Aaron Lear, MD
• Orthopaedic Surgery (Florida)
  • Peter Evans, MD, PhD
  • Carlos Higuera Rueda, MD
  • Joseph P. Iannotti, MD, PhD
  • Brian Leo, MD
  • Leonardo P. Oliveira, MD
  • Michael MacKechnie, MD
  • Jorge Manrique, MD
  • Philipp Streubel, MD
• Rehabilitation and Sports Therapy
  • Gary Calabrese, DPT
  • Richard Kring, PT, DPT, PhD

Diagnostic Services

• Diagnostic Radiology
  • Faysal Altahawi, MD
  • Michael Forney, MD  
  • Maxime Freire, MD
  • Stephen Hatem, MD 
  • Hakan Ilaslan, MD, MBA
  • Josh Polster, MD
  • WanYong Shin, PhD
  • Naveen Subhas, MD 
  • Carl Winalski, MD 
• Nuclear Medicine
  • Frank DiFilippo, PhD
• Pathology
  • Steven Billings, MD
  • John Goldblum, MD
  • Scott Kilpatrick, MD
  • John Reith, MD

Medical Specialty

• Rheumatology and Immunologic Diseases
  • Abby Abelson, MD, FACR
  • Soumya Chatterjee, MD, MS, FRCP
  • Shashank Cheemalavagu, MD
  • Rula Hajj-Ali, MD
  • M Elaine Husni, MD, MPH
  • Sarah Keller, MD
  • Jean Lin, MD, PhD
  • Emily Littlejohn, DO, MPH
  • Brian Mandell, MD, PhD

Neurosciences

• Center for Spine Health
  • Kush Goyal, MD
  • Thomas Mroz, MD
  • Dominic Pelle, MD
• Neurology
  • Yuebing Li, MD, PhD
• Neurosurgery
  • Ghaith Habboub, MD
  • Megan Jack, MD, PhD
  • Michael Steinmetz, MD
• Neurosurgery (Florida)
  • Marc Babi, MD
• Physical Medicine and Rehabilitation
  • Patrick Corrigan, DPT, PhD
  • Joshua Johnson, PT, DPT, PhD
  • Susan Linder

Children's Services

• Center for Pediatric Rheumatology and Immunology
  • Sirada Panupattanapong, MD
  • Angela Robinson, MD
  • Andrew Zeft, MD
• General Pediatrics
  • Ellen Rome, MD, MPH

Hospital Based Care

• Department of Pain Management
  • Jianguo Cheng, MD, PhD
  • Jijun Xu, MD, PhD
• Pulmonary Medicine
  • Amy Attaway, MD

Digestive Disease

• Colorectral Surgery
  • Massarat Zutshi, MD
• Gastroenterology & Hepatology
  • Srinivasan Dasarathy, MD