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Inflammation & Immunity

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About Us

The Department of Inflammation & Immunity advances scientific understanding by bringing together a dedicated and collaborative team of scientists at the forefront of immunologic and organ-based research, to deliver impactful translational science that improves the health and well-being of patients at Cleveland Clinic and across the globe.

Working side-by-side with physicians to study patients and diseases, Inflammation & Immunity scientists address challenging questions to uncover the root causes of inflammatory diseases, and ultimately translate these discoveries into new diagnostic testing, therapies and preventive measures for patients.

More About Us

Research Areas of Focus

Click below to explore labs in our research areas of focus.



Adaptive Immunity Cancer Immunology Inflammation & Fibrosis Innate Host Defense
Mucosal Biology & Epithelial Barriers Signaling & Metabolic Networks Transplant
Featured Lab

Olumuyiwa Awoniyi Lab

The Awoniyi lab studies the microbial mysteries intertwined with primary sclerosing cholangitis and inflammatory bowel diseases.

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Featured Lab

Jayati Basu Lab

The Jayati Basu lab studies the development and biology of innate and adaptive immune cells.

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Featured Lab

Andrea Schlegel Lab

The Andrea Schlegel lab studies the role of mitochondria in transplantation and other diseases.

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Explore all labs in Inflammation & Immunity

Research News

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AI-powered solution developed in collaboration with IBM improves reproducibility in cell culturing

The predictive model, tested in gut epithelial cell samples, provides a path toward benchmarking—not eyeball estimates—in the field.

...
HMGB1 protects our gut by disarming bacterial adhesion

HMGB1 helps prevent bacterial adhesion in the gut, keeping microbes from turning harmful and protecting us from infection and inflammatory disease.

...
Helmsley Trust Awards $2.7M to STAR Consortium for Crohn’s Stricture AI Development

Using advanced imaging and artificial intelligence, the STAR Consortium aims to create an image-based biomarker to drive effective therapies for Crohn’s disease patients with fibrosis.

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Join Us

Exciting investigation and groundbreaking discovery happens every day at Cleveland Clinic. Join our team of expert researchers at the Department of Inflammation & Immunity.

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