Christopher Nguyen Laboratory

Research

Research Support

Mission of Center The mission of CIRC at Cleveland Clinic is the rapid clinical translation of engineering innovations to maximize positive clinical impact for our patients. We strongly believe that research efforts need to be patient-focused and delivery driven. Therefore, we strive to solve healthcare problems which impact patient care, patient accessibility, and patient experience.   Advanced Imaging Clinical imaging is one of the most important diagnostic and prognostic tests available to patients. The investigators at CIRC are at the forefront in the field to develop innovative imaging methods to develop new insights into difficult cardiovascular diseases. We are pioneering new methods to visualize cardiac microstructure to better characterize heart failure, develop accelerated imaging to improve patient accessibility and experience, and innovate interventions to give our patients more treatment options.   Biology-inspired Simulation and Design   Cleveland Clinic has been one of the leaders in innovations for cardiac care, cardiac implants, and cardiac interventions. CIRC stands on the shoulder of giants to bring the latest innovations of biological systems to the bedside. We specialize in patient specific benchtop modeling to optimize care, and next generation implantable devices to optimize patient health outcomes. Combining advanced imaging with novel fabrication techniques, our team is creating highly accurate, made-to-order physical models that replicate an individual's cardiovascular system on a benchtop scale. These models serve as invaluable tools for simulating and studying disease processes at a level of detail that was previously unattainable.   Artificial Intelligence in Medicine Artificial intelligence (AI) is changing the way that we understand and interact with the digital world around us, including in healthcare.  As organizations and tech companies everywhere drive increasingly generalized application of AI, CIRC is focused on ensuring technology is being developed for the benefit of the patients of Cleveland Clinic.  We have specific focus on developing robust clinical data representation, improving patient outcomes using predictive analytics, and thorough validation in practice. We ensure that such tools are developed in safe and ethical manner which not only puts the patient's needs first, but also their privacy and personhood.    Digital Twins for Precision Medicine In the realm of cardiovascular medicine, the advent of digital twins has emerged as a revolutionary paradigm, offering a sophisticated and personalized approach to patient care. A digital twin refers to a virtual replica of an individual's cardiovascular system, meticulously crafted by integrating patient-specific data, such as genetic information, medical history, and imaging results, into a comprehensive computational model. This digital representation provides clinicians with an unprecedented opportunity to simulate and analyze the intricate workings of the cardiovascular system in real-time. By continuously updating and adapting to changes in a patient's health, digital twins enable a dynamic and responsive approach to diagnosis, treatment planning, and monitoring. This transformative technology holds the potential to enhance precision medicine, optimize therapeutic strategies, and ultimately improve patient outcomes in the challenging and nuanced field of cardiovascular health. At CIRC, we are pioneering the fusion of data-driven insights and advanced physics-based simulation technologies to pave the way for more personalized and effective cardiovascular care.   

Selected Publications

View publications for Christopher Nguyen, PhD
(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

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1.   Coll-Font J**, Fan Y, van den Boomen M, Sosnovik DE, Mekkaoui CM, and Nguyen CT^. Manifold-based respiratory phase estimation enables motion and distortion correction of free-breathing diffusion tensor MRI. Magnetic Resonance in Medicine. 2022 Jan;87(1):474-487. doi: 10.1002/mrm.28972. a.  Top selected journal club talk for ISMRM Motion Study Group 2021.  

2.   Snel JHG, van den Boomen M, Hurtado-Ortiz K, Slart RHJA, Van Deursen VM, Nguyen CT, Sosnovik DE, Dierckx RAJO, Velthuis BK, Borra RJH, and Prakken NHJ. Cardiac Alterations on 3T MRI in Young Adults with Sedentary Lifestyle Related Risk Factors. Frontiers Cardiovascular Medicine. 9:840790. 2022 Feb. Doi: 10.3389/fcvm.2022.840790.  

3.   Eder R**, van den Boomen M, Yurista S, Rodriguez-Aviles Y, Islam MR, Chen YC, Trager L, Coll-Font J, Cheng L, Li Habo, Rosenzweig A, Wrann C^, and Nguyen CT^. Exercise-induced CITED4 expression is necessary for regional remodeling of cardiac microstructural tissue helicity. Nature Communications Biology. 5, 656. 2022 May. Doi: 10.1038/s42003-022-03635-y  

4.   Sclocco R, Nguyen CT, Staley R, Fisher H, Mendez A, Velez C, Kettner NW, Kuo B, and Napadow V. Cine gastric MRI reveals altered Gut-Brain Axis in Functional Dyspepsia: gastric motility is linked with brainstem-cortical fMRI connectivity. Neurogastroenterology & Motility. 2022 May. Doi: 10.1111/nmo.14396.  

5.   Shusharina N, Liu X, Coll-Font J, Foster A, El Fakhri G, Woo J, Bortfeld T, Nguyen CT^. Feasibility study of clinical target volume definition for soft tissue sarcoma using muscle fiber orientations derived from diffusion tensor imaging. Phys Med Biol. 67(15). 2022 Jul. Doi: 10.1088/1361-6560/ac8045. PMC9344976  

6.   Klein V, Coll-Font J, Vendramini L, Straney D, Davids M, Ferris NG, Schad LR, Sosnovik D, Nguyen CT, Wald LL, Guerin B. Measurement of magnetostimulation thresholds in the porcine heart. Magn Reson Med. 2022 Jul. Doi:10.1002/mrm.29382  

7.   Yurista S**, Eder R, Welsh A, Chen S, Tang W, and Nguyen CT^. Targeting myocardial substrate metabolism in the failing heart: Ready for prime time? Current Heart Failure Reports. 19(4):180-190. 2022 Aug. Doi: 10.1007/s11897-022-00554-1.  

8.   Yurista SR, Eder R, Yen YF, Farrar CT, Kwon D, Tang WH, Nguyen CT^. Magnetic resonance imaging of cardiac metabolism in heart failure: how far have we come? European Heart Journal: Cardiovascular Imaging. 23, (10) 1277-1289. 2022 Oct.  

9.   Huang M, Akerberg A, Zhang X, Yoon H, Joshi S, Harding C, Nguyen CT, Pu W, Haigis M, Burns CG, and Burns C. Intrinsic myocardial defects underlie an Rbfox deficient zebrafish model of hypoplastic left heart syndrome. Nature Communications. 13, 5877. 2022 Oct. doi.org/10.1038/s41467-022-32982-x  

10.  Rosalia L**, Ozturk C, Fan Y, Coll-Font J, Chen S, Eder R, Kim J, Nagata Y, Levine R, Panagia M, Guerroero J, Mauskapf A, Roche E^, and Nguyen CT^. A soft robotic sleeve mimicking the haemodynamics and biomechanics of left ventricular pressure overload and aortic stenosis. Nature Biomedical Engineering. 6, 11-34-1147. 2022 Oct. doi.org/10.1038/s41551-022-00937-8 a.        Featured on Cover of the October 2022 Issue b.       Pacchioni G. A soft robotic that mimics aortic stenosis. Nature Reviews Materials. 7, 845. 2022.  

11.  Nguyen K, Bonner BP, Foster AN, Sadighi M, Nguyen CT^. Asynchronous magnetic resonance elastography: Shear wave speed reconstruction using noise correlation of incoherent waves. Magnetic Resonance in Medicine. 2022 Oct. doi.org/10.1002/mrm.29502. In Press.  

12.  Illi J, Bernhard B, Nguyen CT, Pilgrim T, Praz F, Gloeckler M, Windecker S, Haberlin A, and Grani C. Translating Imaging into 3D Printed Phantoms - A Systematic Review on Accuracy, Technology, and Validation. JACC BTS. 2022 Oct. doi: 10.1016/j.jacbts.2022.01.002  

13.  Martens P, Nguyen CT, Tang WH. Is epicardial adipose tissue a key pathophysiologic target in heart failure with preserved ejection fraction? J Mol Cell Cardiol. 2022 Oct. doi: 10.1016/j.yjmcc.2022.07.003.  

14.   Kim JH**, Parajuli S**, Sinha A**, Mahamdeh M, van den Boomen M, Coll-Font J, Chen LS, Fan Y, Eder RA, Phipps K, Yuan S, and Nguyen CT^. Pocket CLARITY enables distortion-mitigated cardiac microstructural tissue characterization of large-scale specimens. Frontiers Cardiovascular Medine. 2022 Nov 14. Doi: 10.3389/fcvm.2022.1037500  

15.  Akerberg A**, Huang M, Zhang X, Yoon H, Joshi S, Nguyen CT, Pu W, Burns C, and Burns CG. RBPMS2 is a myocardial-enriched splicing regulator required for cardiac function. Circulation Research. 2022 Nov. 131:980-1000. Doi: https://doi.org/10.1161/CIRCRESAHA.122.321728 a.        Featured on Cover of November 2022 Issue  

16.  Snel GJH, Slart RHJA Slart, Velthuis BK, van den Boomen M, Nguyen CT, Sosnovik DE, van Deursen VM, Dierckx RJH, Borra, RJH, Prakken, NHJ. Interpretation of pre-morbid cardiac 3T MRI findings in overweight and hypertnestive young adults. Plos One. 2022 Dec.   

17.  Weigand-Whitier J, Sedykh, M, Herz, K, Coll-Font J, Foster AN, Gerstner ER, Nguyen CT, Zaiss, M, Farrar, C, Perlman O. Accelerated and Quantitiave 3D Molecular MRI using a Generative Adversarial Network. Magnetic Resonance in Medicine. 2022 Dec. PMID: 36585915  

18.  Djenoune L, Mahamdeh M, Truong T, Nguyen CT, Fraser S, Brueckner M, Howard J, and Yuan S. Cilia function as calcium-mediated mechanosensors that instruct cardiac left-right asymmetry. Science. 2023 January. 379: 71-78. Doi: 10.1126/science.abq7317.  

19.  Rosalia L**, Ozturk C, Goswami D, Bonnema J, Wang S, Bonner B, Puri R, Kapadia S, Weaver J, Nguyen CT^, Roche ET^. Soft robotic patient-specific hydrodynamic model of aortic stenosis and ventricular remodeling. Science Robotics. 2023 Jan. 8 (75): Doi: 10.1126/scirobotics.ade2184. a.        Featured on the Cover of Jan 2023 b.       Featured on CNN 4/1/2022  

20.  Lo Presti, Eck BL, Reyaldeen R, Nguyen CT, Tang WHW, Flamm SD, Seiberlich N, Lima da Cruz G, Prieto C, and Kwon DH. Fingerprinting MINOCA: Unraveling Clues with Quantitative CMR. JACC Case Reports. 2023 Feb 1;7:101722. Doi: 10.1016/j.jaccas.2022.101722.  

21.  Moulin K, Stoeck CT, Axel L, Broncano J, Croiselle P, Dall’Armelina E, Ennis DB, Ferreira PF, Gotschy A, Miro S, Schneider JE, Scott AD, Sosnovik DE, The I, Tou C, Tunniclife EM, Viallon M, Nguyen CT^. In vivo cardiac diffusion imaging without motion-compensation leads to unreasonably high diffusitivity. Journal of Magnetic Resonance Imaging. 2023 Feb. In Press. Doi: /10.1002/jmri.28703     

22.  Bonner B**, Yurista S, Coll-Font J, Chen S, Eder R, Foster A, Nguyen K, Caravan P, Gale E, and Nguyen CT^. Contrast-enhanced cardiac MRI with a manganese-based alternative to gadolinium for tissue characterization of acute MI. Journal of American Heart Association. 2023 April. 12(8). Doi: 10.1161/JAHA.122.026923.  

23.  Yurista S**, Chen S, Eder RA, Garrett T, Butsch WS, Aminian A, Tang WHW, Farrar CT, Gee D, Abel ED, Das S, and Nguyen CT^. Mapping the Unseen: In Vivo CEST-MRI of Creatine Reveals Improved Cardiac Energetics in Subjects with Obesity Following Bariatric Surgery. Obesity Surgery. 2023 June; 33(6):1944-1948. Doi: 10.1007/s11695-023-06589-0.  

24.  Yurista S**, Welsh A, Jiang W, Eder R, Chen S, Bonner B, Foster A, Coll-Font J, Rosenzweig A, and Nguyen CT^. Ketone ester treatment increases cardiac ketone utilization and reduces cardiac inflammation in a porcine model of acute myocardial infarction. Metabolism. 2023 Aug:145:155608. Doi: 10.1016/j.metabol.2023.155608.  

25.  Klein V, Davids M, Vendramini L, Ferris N, Schad L, Sosnovik D, Nguyen CT, Wald L, Bastien G. Predication of experimental cardiac magnetostimulation threwsholds using pig-specific body models.  Magnetic Resonance in Medicine. 2023 Oct;90(4):1594-1609. Doi: / 10.1002/mrm.29717.  

26.  Kodur BS, Yurista S, Province MS, Rueth E, Nguyen CT, and Tang WH, Ketogenic Diet in Heart Failure: Fact or Fiction? JACC: Heart Failure. 2023 July. Doi: / 10.1016 /j.chf.2023.05.009.  

27.  Kim D, Coll-Font J**, Lobos RA, Stab D, Pang J, Foster A, Garret T, Bi X, Speier P, Haldar JP, Nguyen CT^. Single breath-hold CINE imaging with combined simultaneous multislice and region-optimized virtual coils. Magnetic Resonance in Medicine. 2023 Jul; 90(1):222-230. Doi: 10.1002/mrm.29620.  

28.  Joy G, Webber M, Kelly C, Webber M, Pierce I, Teh I, McGraph L, Velazquez, Hughes RK, Kotwal H, Das A, Chen F, Bakalakos A, Lorenzini M, Savvatis K, Mohiddin SA, Macfarlane PW, Orini M, Manisty C, Kellman P, Davies RH, Lambiase PD, Nguyen CT, Schneider JE, Tome M, Captur G, Dall'Armellina E, Moon J, and Lopes LR. Microstructural and Microvascular Phenotype of Sarcomere Mutation Carriers and Overt Hypoertrophic Cardiomyopathy. Circulation. 2023 Jul. 148:808-818. Doi: 10.1161/CIRCULATIONAHA.123.063835.  

29.  Yurista S, Eder R, Feeley M, Kodur N, Tang WH, and Nguyen CT^. A closer look at AHA/ACC and ESC Guidelines for Managing Obesity and Overweight in Adults. JACC Advances. 2023 Sep. 2 (7). Doi: 10.1016/j.jacadv.2023.100570.  

30.  Shusharina N, Nguyen CT^. Consistency of muscle fibers directionality in human thigh derived from diffusion weighted MRI. Phys Med Biol. 68. 2023 Sep. Doi: 10.1088/1361-6560/acf10c  

31.  Qiu J, Huang P, Nakashima M, Lee J, Zhu J, Tang W, Chen P, Nguyen CT, Kim BH, Kwon D, Weber D, Zhao D, Chen D. Multimodal Representation Learning of Cardiovascular Magnetic Resonance Imaging. Machine Learning for Multimodal Healthcare Data (PMLR, 2023).  

32.  Nakashima M, Salem D, Tang WHW, Nguyen CT, Hwang TH, Zhao D, Kim BH, Kwon D, Chen D. Reducing Contextual Bias in Cardiac Magnetic Resonance Imaging Deep Learning Using Contrastive Self-Supervision. Machine Learning for Healthcare Conference vol. 219 (PMLR, 2023).  

33.  Singh M, Bonnemain J, Ozturk C, Saeed MY, Rowlett M, Park C, Fan Y, Nguyen CT, Roche ET. Robotic Right Ventricle (RRV): A biohybrid platform simulating structure, contractility, and fluid dynamics of right ventricular physiology, dysfunction, and intervention. Nature Cardiovascular Research. 2023 Dec. 2, 1310-1326. Doi: 10.1038/s44161-023-00387-8. a.  News https://www.news-medical.net/news/20231213/Innovative-robotic-right-ventricle-developed-to-mimic-heart-biomechanics.aspx b.  News https://medicalxpress.com/news/2023-12-robotic-replica-heart-chamber.html  

34.  Park C, Singh M, Saeed MY, Nguyen CT, Roche ET. A high-fidelity biorobotic cardiac benchtop simulator for testing mitral valve repair and replacement technologies. Devices. 2024 Jan. (2)1. Doi: 10.1016/j.device.2023.100217. a.        Cover on January 2024 Issue  

35.  Sadighi M**, Kara D, Mai D, Nguyen CT^. Cardiac diffusion tensor imaging using short axis PROPELLER: A feasibility study. Magnetic Resonance in Medicine. 2024 Jan. Doi: 10.1002/mrm.30020.  

36.  Kwon D, Huang S, Turkmani M, Salam D, Al-Dieri D, Wang TKM, Kapadia S, Krishnaswamy A, Gillinov M, Svesson LG, Tang WHW, Chen D, Nguyen CT, Wang X. Cardiac MRI-Enriched Phenomapping Classification and Differential Treatment Outcomes in Patients with Ischemic Cardiomyopathy. Circulation Cardiovascular Imaging. 2024 Feb. 17(4). Doi: 10.1161/circimaging.123.016006.  

37.   Anthony C, Wang TKM, Sala D, Obuchowski N, Turkmani M, Al-Deiri D, Popovic Z, Griffin B, Flam S, Chen D, Nguyen CT, Tang WH, and Kwon D. Impact of Cardiac Magnetic Resonance Left Atrial Ejection Fraction in Advanced Ischemic Cardiomyopathy. JACC Advances. 2024 Feb. 3(2). Doi: 10.1016/j.jacadv.2023.100796.  

38.   Martens P, Ives L, Nguyen CT, Kwon D, Hanna M, Tang WHW. The Impact of Iron Deficiency on Disease Severity and Myocardial Function in Cardiac Amyloidosis. American Journal of Medicine Open. 2024 Feb. Doi: 10.1016/j.ajmo.2023.100063.  

39.   Saouaf R, Xie Y, Kim S, Raphael Y, Nguyen CT, Luthringer DJ, Daskivich TJ, Lo E, Tighiouart M, Li D, Kim HL. High-Resolution Diffusion-Weighted Imaging to Detect Changes in Tumor Size and ADC, and Predict Adverse Biopsy Histology During Prostate Cancer Active Surveillance. Cancer Research Communications. 2024 March. Doi: 10.1158/2767-9764.CRC-24-0009.  

40.    Kara D**, Koenig K, Lowe M, Nguyen CT^, Sakae K. Facilitating diffusion tensor imaging of the brain during continuous gross head motion with first and second order motion compensating diffusion gradients. Magnetic Resonance in Medicine. 2024 Apr. 91(4):1556-1566. Doi: 10.1002/mrm.29924.

41.    Goswami D**, Kazim M, and Nguyen CT^. Applications of 3D Printing Technology in Diagnosis and Management of Heart Failure. Current Treatment Options in Cardiovascular Medine. 2024. In Press.    

42.    Rosalia L, Wang SX, Ozturk C, Huang W, Bonnemain J, Beatty R, Duffy GP, Nguyen CT, Roche ET. Soft robotic platform for progressive and reversible aortic constriction in a small-animal model. Science Robotics. 2024 Jul. 9, eadj9769. Doi: 10.1126/scirobotics.adj9769.  

43.    Simkowski J, Eck B, Tang WHW, Nguyen CT, Kwon DK. Next-Generation Cardiac Magnetic Resonance Imaging Techniques for Characterization of Myocardial Disease. Current Treatment Options in Cardiovascular Medicine. 2024 Aug. https://doi.org/10.1007/s11936-024-01044-4.  

44.    Wang TK, Kocyigit D, Chan N, Salam D, Turkmani M, Bullen J, Popovic ZB, Nguyen CT, Griffin BP, Tang WHW, Kwon DK. Prognosis and Predictors of Right Ventricular Dysfunction by Quantitative Cardiac Magnetic Resonance in Non-ischemic Cardiomyopathy. European Heart Journal Cardiovascular Imaging. 2024 Aug. In Press.  

45.    Kara D**, Liu Y, Chen S, Garrett T, Younis A, Sugawara M, Bi X, Wazni O, Nakagawa H, Kwon DH, Nguyen CT^. In vivo cardiac diffusion tensor imaging on an MR system featuring ultra-high performance gradients with 200 mT/m maximum gradient strength. Magnetic Resonance in Medicine. 2024 Sept. In Press.  

46.    Dall’Armellina E, Ennis DB, Axel L, Croisselle P, Ferreira PF, Gotschy A, Lohr D, Moulin K, Nguyen CT, Nielles-Vallespin S, Romero W, Scott AD, Stoeck C, Teh I, Tunnicliffe L, Viallon M, Wang V, Young AA, Schneider JE, Sosnovik DE. Cardiac diffusion-weighted and tensor imaging: a Socieity for Cardiovascular Magnetic Resonance (SCMR) special interst group consensus statement. 2024 Oct. Journal of Cardiovascular Magnetic Resonance. In Press. Doi: https://doi.org/10.1016/j.jocmr.2024.101109.  

47.    Ozturk C, Pak DH, Rosalia L, Goswami D, Robakowski ME, McKay R, Nguyen CT, Duncan JS, Roche ET. AI-powered multi-modal modeling of personalized hemodynamics in aortic stenosis. Advanced Science. 2024 Nov. In press. Doi: 10.1002/advs.202404755.  

48.    Cockrum J, Nakashima M, Ammoury C, Rizkallah D, Mauch J, Lopez D, Wolinsky D, Hwang TH, Kapadia S, Svensson LG, Grimm R, Hanna M, Tang WHW, Nguyen CT, Chen D, and Kwon D. Leveraging a Vision Transformer Model to Improve Diagnostic Accuracy of Cardiac Amyloisis with Cardiac Magnetic Resonance. JACC Imaging. 2024 Dec. Doi: 10.1016/j.jcmg.2024.09.010  

49.    Kiang A, Al-Dieri D, Wang TKM, Nezafat R, Rizkalllah D, Callahan T, Lee J, Santangeli P, Wazni O, Varma N, Nguyen CT, Sroubek J, and Kwon D. Late-gadolinium enhancement predicts appropriate device herapies in non-ischemic recipients of primary prevention implantable cardioverter -defibrillators. Heart Rhythm. 2025 Jan. Doi: 10.1016/j.hrthm.2025.01.003.  

50.    Liu Y**, Kara D, Garrett T, Chen S, Wee D, Jin N, Speier P, Nakagawa H, Santangeli P, Bolen MA, Wazni O, Hanna M, Tang WHW, Tandon A, Kwon D, Bi X, and Nguyen CT^. Towards Optimal Inline Respiratory Motion Correction for In Vivo Cardiac Diffusion Tensor Magnetic Resonance Imaging Using Symmetric and Inverse-Consistent Deformable Image Registration. Magnetic Resonance in Medicine. 2025 Jan. In Press  

51.    Kodur N, Nguyen CT, Tang WHW. Therapeutic Ketosis for Heart Failure: A State-Of-The-Art Review. Journal of Cardiac Failure. 2025 Jan. In Press.

52.    Kodur N, Nguyen CT, Tang WHW. Management of Heart Failure with Improved Ejection Fraction: Current Evidence and Controversies. JACC: Heart Failure. 2025 Feb. In Press.  

53.    Kocyigit D, Obuchowski N, Ho N, Popvic Z, Chen D, Nguyen CT, Tang WHW, Kwon D. Sex Differences in Cardiac Remodeling in Ischemic Cardiomyopathy and Functional Mitral Regurgitation: Impact on Prognosis. European Heart Journal Imaging Methods and Practice. 2025 Feb. In Press.

54.    Sun X, Nakashima M, Nguyen CT, Chen PH, Tang WHW, Kwon D. FairICP: Identifying Biases and Increasing Transparency at the Point of Care in Post-Implementation Clinical Decision Support using Inductive Conformal Prediction. J Am Med Inf Assoc. 2025 Apr. In Press.  

55.    Dos Santos K, Yurista SR, Mirrione SM, Guarin Bedoya DO, Calos SR, Luptak I, Takahashi AM, Tang WHW, Iwamoto Y, Nguyen CT^, Yen Yi-Fen^. Hyperpolarized 1-13C pyruvate MRSI reveals a diet-dependent metabolic shift in ZSF1 rats. Journal of Magnetic Resonance Open. 2025 Jul. In Press.

  56.    Rizkallah D, Greenberg NL, Khurana R, Palanisamy V, Alencherry B, Ammoury C, Salam Y, Lamovsky L, Fares H, Gesche R, Grimm R, Nguyen CT, Chen D, Kwon DH. Impact of Automated Transfer of Semi-Automated Segmentation and Structured Report Rule Requirements on Cardiac MRI Report Quality, Standardization, and Efficiency. AMIA Annu Smp Proc. 2025 Jul. In Press  

57.    Teh I, Ferreira P, Absil J, Afzali M, Agger P, Akbari B, Alteras A, Aono S, Benton C, Bhattacharya S, Croiselle P, De Bruecker Y, Dall’Armellina E, Ennis DB, Glessgen C, Glinska A, Haltmeier S, Hannum A, Hedstrom E, Hussein T, Jones S, Joy G, Kettless K, Kim WY, Kozerke S, Magat J, Muthupillai R, Nezafat R, Nielles-Vallespin S, Oshinski J, Ozenne V, Pennell DJ, Pettigrew R, Pierce I, Raman B, Sabisz A, Schnieder JE, Sherman JH, Shetye A, Thoma P, Treibel T, Tsuneta S, Valleee JP, Vejstrup N, Viallon M, Nguyen CT, Scott AD, Stoeck CT. Multi-centre Investigation of Cardiac Diffusion Tensor Imaging in Healthy Volunteers by SCMR Cardiac Diffusion Special Interest Group Network (SIGNET). J Cardio Magn Reson. 2025 Aug. In Press.  

58.    Coveney S, Shelley D, Foster RJ, Afzali M, Poenar AM, Sharrack N, Plein S, Dall’Armellina E, Schneider JE, Nguyen CT^, Teh I^. Optimizing Cardiac Diffusion Tensor Imaging In Vivo: More Directions or Averages? J Cardio Magn Reson. 2025 Aug. In Press.  

59.    Chen S**, Kara D, Coll-Font J, Garret T, Eder R, Foster A, Yurista S, Tandon AA, Wazni O, Tang WHW, Kwon D, and Nguyen CT^. Characterization of Normal Myocardial Microstructure for Healthy Women and Men Cohorts using cDTI with Ultra-High-Performance Gradient MRI Scanner. J Cardio Magn Reson. 2025 Sept. In Press.  

60.    Sclocco R, Coll-Font J, Kuo B, Napadow V, Nguyen CT^. GLOW: Gastic LOW-rank tensor-based motion correction for abdominal 4D MRI. NMR Biomedicine. 2025 Sept. In Press.  

61.    Laghzali O**, Kara D, Chen S, Liu S, Shalikar S, Rusu MC, Qadri F, Carrier L, Yang HJ, Niendorf T, Ku MC^, Nguyen CT^. Translational Insights into Myocardial Deformation and Fibrosis in Hypertrophic Cardiomyopathy Using Diffusion Tensor MRI. JACC Advances. 2025 Oct. In Press.  

62.    Fang MZ, Nakashima M, Singh K, Galvani E, Sun X, Sorathia S, Dorocak K, Kwon D, Nguyen CT, Chen D. CMR-LLAMA: a Finetuned Large Language Model for Identifying Findings and Associated Attributes in CMR Reports. Journal of Cardiovascular Magn Reson. 2025 Oct. In press  

63.    Deshmukh T, Hume RD, Chen Siqi, Igoor Sindhu, Foster SL, Barry T, Lu J, Tran V, Pouliopoulos J, Jabbour A, Vigder A, Cordwell SJ, Tumanov S, Nguyen CT, Kotake Y, Turnbull S, Campbell T, Pathan F, Kumar S, Kizana E, Chong JJH. Npj Regnerative Medicine 10, 46. 2025. Doi.org/10.1038/s41536-025-00433-y. In press.  

64.    Mai D**, Kara D, Liu Y, Moura TRS, Sadighi M, Kanj F, Wexler E, Sosnovik D, Hanna M, Santangeli P, Nakagawa H, Wazni O, Chen D, Tang WHW, Tandon A, Kwon D, Nguyen CT^. Free-breathing multi-slice co-registered cardiac T1, T2 and ADC mapping with spin-echo plan imaging. Magn Reson in Med. 2025 Nov. In Press.  

65.    Moura TRS**, Mai D, Wexler E, DeAngelo L, Houston A, Kohut K, Abuirmaileh W, Roselli EE, Kwon DH, Chen D, Kara D, Nguyen CT^. Feasibility study for dual phase free breathing 3D bSSFP MRA with preserved eddy-current tolerance with adaptive k-space lengths (PETAL) acquisition. Magn Reson in Med. 2025 Nov. In Press.  

66.    Asad MEHAK, Joy G, Lwin M, Nguyen CT, Lopes L, Teh I, Soo C, Anderton T, Borg L, Chambers B, Swoboda P, Moon J, Plein S, Schneider J, Dall’armellina E. Diagnostic performance of cardiac diffusion tensor imaging in subclinical hypertrophic cardiomyopathy: a comparision with strain analysis. European Heart Journal. 46(1), ehaf784.239. 2025 Nov. Doi.org/10.1093/eurheartj/ehaf784.239.  

67.    Korkerdsup T, Wang TKM, Ammoury C, Rizkallah D, Chen D, Nguyen CT, Tang WHW, Kwon D. Impact of Cardiac Magnetic Resonance Prediction of Left Ventriular Filling Pressure to Predict Adverse Outcomes in Non-ischemic Cardiomyopathy. European Heart Journal Cardiovascular Imaging. 2025 Nov. In Press.  

68.    Black C, Calcagno T, Liu Y, Bi X, Lockwood D, Jeanblanc G, Harris R, Wu J, Pasquale S, Sroubek J, Higuchi K, Chung R, Wazni O, Nguyen CT, Kwon D. Impact of Wideband Phase Sensitive Inversion Recovery Motion Corrected Late Gadolinium Imaging on 3T Cardiac Magnetic Resonance Image Quality and Diagnostic Utility in Patients with Cardiac Implantable Electronic Devices. Hearth Rhythm O2. 2025 Dec. In Press.  

69.    Kanj F**, Kara D, Garrett T, Mai D, Hanna MA, Kwon D, Nguyen CT^. Diffusion tensor cardiac magnetic resonance may detect early cardiac amyloidosis in carpal tunnel syndrome. JACC Advances. 2025 Dec. In Press  

70.    Translating Mechanistic Insights into Action and Revealing New Pathways: Machine Learning Approaches in Heart Failure with Preserved Ejection Fraction. Journal AHA. 2026 Jan. In Press.  

71.    Varela CE, Monahan DS, Fan Y, Islan S, Kelleher JT, Whyte W, Bonnemain J, Ngoy S, Fisch S, Wallace E, Ronan W, Beatty R, Dolan EB, Nguyen CT, Duff GP, Roche ET. Biomaterials. 2026 Feb. In Press.  

72.    Vora N, Cook M, Harper L, Nguyen CT, Bolen S, Bolen M. Scoping Review of Cardiac Diffusion MRI: What’s Been Done, and Where to Next. Radiology CT Imaging. 2026 March. In Press.  

73.    Wang Q, Zhang W, Chen J, Stenson K, Parsai S, Parthasarathy P, Liu CF, Garrett T, Lin J, Hou A, Shimpi R, Gu E, Yin M, Shannon L, Johnson S, Willard B, Rodriguez E, Androjna C, Moudgil R, Sun Y, Yu J, Nguyen CT, Alban T, Chan T, Prsad S, Tang WHW, Lin J, Zhao J. Novel Mechanism and Therapy of Anthracycline-Induced Cardiotoxcity (AIC). Cancer Research Communications. 2026 March. In Press.  

74.    Nakashima M, Qiu J, Huang P, Lee J, Chen PH, Grimm R, Nguyen CT, Kim BH, Zhao D, Kwon D, and Chen D. CMR-CLIP: Contrastive Language Image Pretraining for a Cardiac Magentic Resonance Embedding with Zero-Shot Capabilities. Nature Communications. 2026 March. In Press.  

75.    Chan FTS, Coveney S, Zheng SL, Webber M, Joy G, Shiwani H, Topriceanu CC, Falconer D, Martin E, Ahmad M, Stanley M, Vrapi F, Makharia MK, Karia N, Nouriel H, Whelan C, Tomson J, Khiani R, Chaturvedi N, Orini M, Pierce I, The I, Schneider J, Nguyen CT, Hughes AD, Moon JC, Lambiase PD, Kellman P, Dall’Armellina E, Captur G. Microstructural disease and hypoperfusion in dilated cardiomyopathy associated with ventricular arrhythmias and underpin midwall septal fibrosis. JCMR. 2026 April. In Press.  

76.    Alexandrino FB, Curtis B, Nguyen CT, Kwon D, Ramchand J, Tang WHW. Filamin C Genetic Cardiomyopathy Presenting as Acute Myocardial Injury. JACC Case Reports. 2026 April. In Press.